ISSN 1518 0557
Recurrent germinal vesicle resistant to in vitro maturation: case report

2012; 16
Nícolas Thiago Nunes Cayres de Souza, Hitomi Miura Nakagava, Íris de Oliveira Cabral, David Barreira Gomes Sobrinho, Antônio César Paes Barbosa, Bruno Ramalho Carvalho
JBRA Assist. Reprod. 2012; 16 (5):286-289

Received November 12, 2012
Accepted December 12, 2012
Abstract

The identification of the germinal vesicle (GV) of oocytes following stimulation for in vitro fertilization (IVF) suggests maturation arrest in prophase I stage of meiosis, identifiable by the observation of compact typical nucleolus. The cancellation of IVF cycles associated to persistence of GV is a frustrating experience for the infertile couple and the whole staff. It remains an unpredictable challenge for reproductive health services, with a few cases reported. We present a case of recurrent immature oocyte retrieval with all of them immature after controlled stimulation for IVF, followed by total failure of in vitro maturation (IVM), in a young patient with endometriosis.


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doi: 10.5935/1518-0557.2012.16.5.06

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