Fernando Zegers-Hochschild, Juan Enrique Schwarze, Javier Crosby, Carolina Musri, Maria do Carmo Borges de Souza
JBRA Assist. Reprod. 2012; 16 (6):320-328
Received December 10, 2012
Accepted December 17, 2012
Abstract
Background:This 2st report represents the results of ART procedures performed during 2010 by 140centers from 13countries in Latin America.Furthermore, this is the first time, a multinational registry is performed on a case-by-case bases.
Methods:All centers reported their ART procedures electronically and their data was accepted after consistency checks were performed and the institution, certified by an accreditation team.A total of 37,853 initiated ART cycles included 3,731IVFcycles; 22,637ICSIcycles; 5,157FET and 6,320ODembryo transfers, plus 8 cases of GIFT, which are not described in this report.
Results:The majority(39%) of ET in IVF/ICSI cycles were performed in women age 35-39years.The delivery rate(DR) per OPU in ICSI and IVF cycles were 28.8% and 30.9%, respectively.The multiple delivery rates in IVF/ICSI cycles were 23.9%(22.1% twins and 1.8% triples).When ≥2embryos were transferred, neither the CPR nor the proportion of twins increased significantly.However, the proportion of triplet increased significantly when ≥3embryos were transferred.In OD cycles, twin and triplet deliveries were 25.4%and2.2%, respectively.In FET cycles, twin and triplet deliveries were 17.6% and 1.5%, respectively.Multiple deliveries were associated with a significant increase in preterm delivery and perinatal mortality. The CPR was 18% with eSET and 43% with eDET.In women aged ≤34years, CPR with eSET was 30% and 52% with eDET.In OD cycles, the CPR with eSET was 29%, and 52% with eDET.
Conclusions:Overall, delivery rates are comparable to most developed countries in the world.However, REDLARA has to enforce the reduction in the number of embryos transferred in IVF/ICSI and OD cycles, in order to prevent multiple births and decrease the corresponding perinatal complications.